Hyperemesis Gravidarum Vomiting—especially during the first trimester—is normal for many women during pregnancy. Constantly vomiting is not. Take action to prevent a serious complication. Cholestasis of Pregnancy Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is slowed or stopped resulting in itching and jaundice. Acute Fatty Liver of Pregnancy Acute fatty liver of pregnancy is a rare, but serious, condition of pregnancy in which there is an excessive accumulation of fat in the liver or liver cells.