Metabolic Syndrome Most people who have metabolic syndrome have insulin resistance. This may be a beginning of the development of type 2 diabetes. Type 2 Diabetes A person with type 2 diabetes either can't make enough insulin or can't properly use it. Sleep Apnea Sleep apnea is a breathing disorder in which a person experiences brief interruptions of breathing during sleep. Gastroesophageal Reflux Disease (GERD)/Heartburn Gastroesophageal reflux is the return of acidic stomach juices, or food and fluids, back up into the esophagus.