Overview of Multiple Pregnancy Multiple pregnancy is a pregnancy with two or more fetuses. In the United States, the multiple birth rate is rising. Symptoms and Diagnosis of Multiple Pregnancy Every pregnant woman feels like she’s getting big, but if you’re pregnant with two or more babies, you’ll really be growing fast. Be prepared by learning the signs of a multiple birth. Complications of Multiple Pregnancy Having more than one baby is especially exciting—and complicated. Find out what to watch for, including a greater chance of anemia and preterm birth. Care and Management of Multiple Pregnancy A woman with a multiple pregnancy needs more calories and nutrients, more frequent prenatal visits, and more rest. Newborn Multiples Because many multiples are small and born early, they may be initially cared for in a special care nursery called the neonatal intensive care unit.